Bacteriocin: carnocin UI49
Accession: BAC001
Classification
Class: lantibiotic
Genetics
Gene: Unidentified
Producer and target organisms
Producer Organism: Carnobacterium sp (strain UI49) [Gram-positive]
Taxonomy: Bacteria
FirmicutesLactobacillalesCarnobacteriaceaeCarnobacterium
Target organismsCarnobacteria - Lactobacilli - Pediococci - Lactococci
Description
Mode of action:
Lanthionine-containing peptide antibiotic (lantibiotic). Active on Gram-positive bacteria.
Lanthionine-containing peptide antibiotic (lantibiotic). Active on Gram-positive bacteria.
Uniprot and PDB links
UniProt Entry: P36960
PDB EntryUnknown
NULL
MEDLINE=92321768;PubMed=1622206;
Stoffels G., Nissen-Meyer J., Gudmundsdottir A., Sletten K., Holo H., Nes I.F.
"Purification and characterization of a new bacteriocin isolated from a Carnobacterium sp.", Appl Environ Microbiol 58 (5):1417-22(1992).
MEDLINE=92321768;PubMed=1622206;
Stoffels G., Nissen-Meyer J., Gudmundsdottir A., Sletten K., Holo H., Nes I.F.
"Purification and characterization of a new bacteriocin isolated from a Carnobacterium sp.", Appl Environ Microbiol 58 (5):1417-22(1992).
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Protein sequence
| ........10 | GSEIQPR |
Warning: partial sequence.
Wheel representation
Protein sequence annotations
| Feature | Position(s) | Length | Description |
| PEPTIDE | 1 | Lantibiotic carnocin-UI49. Feature identifier = PRO_0000045088. | |
| NON_TER | 7 |
Composition
Hydrophobicity
Composition
| Formula | C32
H55
N11
O12
|
| Absent amino acids | ACDFHKLMNTVWY |
| Common amino acids | EGIPQRS |
| Mass (Da) | 803.95 |
| Net charge | 0 |
| Isoelectric point | 6.41 |
| Basic residues | 1 |
| Acidic residues | 1 |
| Hydrophobic residues | 1 |
| Polar residues | 2 |
| Aliphatic residues | 1 |
| Tiny residues | 2 |
| Boman Index | -24.81 |
| Hydropathy Index | -1.4 |
| Aliphatic Index | 55.71 |
| Instability Index | 80.34 (unstable) |
| Half Life |
Mammalian : 30 hour Yeast : >20 hour E. coli : >10 hour |
| Extinction Coefficient | 0 M-1 cm-1 |
| Absorbance 280nm | 0 |
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